Hepatoprotective Potential of Methanolic and Aqueous Extract of Chenopodium botrys against Lead-induced Toxicity

Background: Chenopodium botrys L. is local to Europe and Asia established in North America. The plant commonly used for the treatment of disease. medicinal use mainly due mythology rather than scientific proof. Objectives: To evaluate hepatoprotective potential methanolic aqueous extract against lead-induced toxicity. Materials Methods: aerial parts were extracted by continuous hot extraction process using acetone methanol as a solvent plants obtained cold maceration process. Liver tissue was treated with 5 ppm Lead Acetate mg/ml botrys. During study, biochemical indices like lipid peroxidation (LPO), Protein levels enzymatic activities alkaline phosphatase (ALPase), acid (ACPase) succinate dehydrogenase (SDH) measured. Results: current study report that protein parameters well declined significantly while increased lead acetate exposed goat liver homogenates compared control groups. Co-administration herbal (5 mg/ml) along homogenate exerted an ameliorative effect maintained studied closed group. Conclusion: endowed activity. It can be taken one candidate development agents because its good safety profile.